Andheri East sits on the Western Express Highway and is served by Andheri Railway Station (Western & Harbour lines), among Mumbai's busiest stations. Three Metro lines converge here: Blue Line 1 (Versova-Ghatkopar) with stops at Andheri, WEH, Chakala, Airport Road and Marol Naka; Red Line 7 to Dahisar East; and the underground Aqua Line 3 via SEEPZ/Marol Naka, extended to Cuffe Parade/BKC in October 2025.

The airport is about 3 km away via Sir M.V. Road.

Andheri East hosts a cluster of K-12 schools around Chakala, Gundavali and Mahakali Caves Road, including Canossa High School, Holy Family High School, Divine Child High School and St. Dominic Savio High School.

IIT Bombay lies roughly 8 km away in adjoining Powai, outside the locality itself.

Andheri East is anchored by SEEPZ, the Santacruz Electronics Export Processing Zone set up in 1973 as India's first export-processing zone; it now hosts 400+ electronics, software and gems/jewellery units, including TCS and CGI.

Adjoining Marol MIDC and Chakala Industrial Area add manufacturing, IT/ITES offices and corporate parks, making the locality one of Mumbai's principal employment hubs alongside its housing stock.

Tourism draws are modest and heritage-led. The Mahakali (Kondivite) Caves, a complex of 19 rock-cut Buddhist monuments dated between the 1st century BCE and 6th century CE, lie within Andheri East and are.

Andheri (east and west) also has a long film/TV studio legacy dating to the 1930s-80s.

Andheri (spanning both East and West) has a long-standing reputation as a hub for film studios and TV production.

Andheri East falls under BMC's K/East ward, which also covers Jogeshwari East and Vile Parle East, per MCGM's official ward records. The locality is built around the Western Express Highway and has gained three Metro lines in the past decade.

Recurring civic challenges include traffic congestion around Andheri station and Andheri-Kurla Road, and monsoon waterlogging in low-lying stretches.